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Neuromuscular Bioengineering Laboratory

Our Research Focus

Our lab studies the function, dysfunction, and plasticity of the nervous and muscular systems. We utilize a cross-disciplinary approach at molecular, cellular, and tissue scales to address the following research priorities:

  • To enhance surgical decision-making and the development of physical therapy protocols by understanding relationships between the ultrastructure of peripheral nerves and their mechanical and physiological function.
  • To develop tissue engineering and biomedical device-based strategies for peripheral nerve regeneration.
  • To reveal mechanisms guiding the remodeling of neuromuscular junctions.
  • To elucidate mechanisms underlying the transport and remodeling of the axonal cytoskeleton.
  • To understand mechanical influences on the morphology and function of neurons in the central nervous system.


Sameer B. Shah, Ph.D.

Sameer B. Shah, Ph.D.
Departments of Orthopaedic Surgery & Bioengineering
UC San Diego
9500 Gilman Drive, Mail Code 0863
La Jolla, CA 92093-0863

Office: (858) 822-0720
Fax: (858) 822-3807